Paganini first learned to play the mandolin from his father at the age of five before moving on to the violin. He began composing at seven and, by the age of 12, he was performing publicly. At the age of sixteen, Paganini had a breakdown of sorts and disappeared into alcoholism. Eventually, with the aid of an unnamed female benefactor, he managed to quit drinking. Once sober, he sequestered himself away for three years and studied the violin obsessively. When he returned to the public eye at the age of 22, he became the first music superstar.

Paganini was capable of playing three octaves across four strings in a hand span, a nearly impossible feat, even by today's standards. His flexibility and exceptionally long fingers have resulted in speculation that he may have had Marfan syndrome, a genetic mutation not identified until 1899 that results in elongated fingers and other unique traits. Others have conjectured that he had Ehlers-Danlos syndrome, commonly know as Rubber Man Syndrome, and still other attribute his abilities to his instrument – dubbed The Cannon.

In the early 1830’s Paganini’s health began to rapidly deteriorate. But 1834 he was no longer had the stamina to play his violin and he retired from public performance. The great violinist to ever live died in Nice on May 27, 1840.